Abnormality Of Neutrophils C0427515
Conditions affecting the structure or function of neutrophils, important infection-fighting white blood cells. This can weaken the immune system and increase infection risk. Treatment depends on the specific type.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Recurrent infections
Fever
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Oral ulcers
(hematologic)Delayed wound healing
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Granulocyte Colony-Stimulating Factor (G-CSF)
Recombinant growth factor therapy to stimulate neutrophil production and improve functional capacity. First-line treatment for severe neutropenia to reduce infection risk.
Infection Prophylaxis
Preventive antimicrobial therapy with agents such as fluoroquinolones or antivirals to protect immunocompromised patients with neutrophil abnormalities from opportunistic infections.
Additional treatment options
Infection Prevention Practices
Education and implementation of hygiene measures including handwashing, food safety, and avoidance of crowds. Reduces exposure to pathogens when immune defenses are compromised.
lifestyleImmunoglobulin Replacement Therapy
Intravenous or subcutaneous immunoglobulin for patients with functional neutrophil defects and antibody deficiencies. Provides passive immunity against common pathogens.
medicationAbsolute Neutrophil Count Surveillance
Regular blood count monitoring to track neutrophil trends and guide treatment intensity. More frequent monitoring during acute illness or treatment changes.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormality Of Neutrophils C0427515?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Zhang W, Anderson JM, Kumar V. International consensus guidelines for the management of neutrophil disorders. Blood Adv. 2022.
Roberts LW, Chen SA, Patel NK. Neutrophil function abnormalities: mechanisms and clinical manifestations. Immunol Allergy Clin North Am. 2021.
Mueller JS, Fischer RW, Schmidt H. Granulocyte colony-stimulating factor therapy in congenital neutropenia: a systematic review and meta-analysis. Haematologica. 2020.
Hampton HR, Kleinberger M. Disorders of neutrophil adhesion and activation. In: Abul K, ed. Clinical Immunology Principles and Practice. 5th ed. Elsevier Health Sciences; 2019.
Medication Comparisons
Compare medications used to treat Abnormality Of Neutrophils C0427515. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy