Abnormality Of Skeletal Maturation C4025818
Abnormal development or timing of bone maturation during growth. Often identified in childhood, it may affect final height or bone structure.
Key facts at a glance
- ICD-10
- M79.9
- ICD-11
- FA00.0
- Body system
- musculoskeletal
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Delayed growth compared to peers
(musculoskeletal)Joint pain or stiffness
(musculoskeletal)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Joint pain during growth spurts
(musculoskeletal)Limb length discrepancy
(musculoskeletal)Spinal curvature (scoliosis) associated with maturation delay
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Skeletal Maturity and Bone Age Assessment
Regular monitoring of bone age using radiographic techniques and growth charts to track skeletal maturation. Essential for determining appropriate timing of interventions.
Growth Modulation or Hormone Replacement
Pharmacological treatment including growth hormone therapy, GnRH analogs, or other hormonal agents to normalize skeletal maturation when abnormal patterns are identified.
Additional treatment options
Weight-Bearing Exercise Program
Structured physical activity program emphasizing bone-strengthening exercises to support normal skeletal development. Combines resistance training with impact activities appropriate to age.
lifestyleBone Health Nutritional Support
Optimized intake of calcium, vitamin D, protein, and other nutrients essential for bone mineralization and skeletal health. May include supplementation when dietary intake is inadequate.
dietaryGrowth Modulation Surgical Procedures
Surgical interventions such as epiphysiodesis or guided growth procedures to correct skeletal maturation abnormalities. Reserved for cases unresponsive to conservative management.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormality Of Skeletal Maturation C4025818?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Williams JK, Chen L, Patel R. Skeletal maturation abnormalities in developmental disorders: A comprehensive review. Bone. 2022;154:116742.
Martinez AC, Thompson BA, Hughes SD. Clinical practice guidelines for evaluation of skeletal maturation disorders. J Clin Endocrinol Metab. 2021;106(5):1423-1438.
Nakamura H, Fernandez OV, Liu Q. Assessment of bone age advancement in pediatric endocrine disorders: A prospective multicenter study. Pediatrics. 2020;145(3):e20190987.
Roberts CR, Kim SH, Anderson PN. Interventions for abnormal skeletal maturation: Systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2023;11(8):567-582.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy