Acinar Prostate Adenocarcinoma Signet Ring Variant C5787291
An uncommon and aggressive form of prostate cancer where cells have a distinctive appearance. It mainly affects men and tends to spread more quickly than typical prostate cancers. Treatment follows standard prostate cancer protocols.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Urinary obstruction
(oncologic)Hematuria
(oncologic)Unexplained weight loss
(oncologic)Pathologic bone fracture
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical Prostatectomy with Lymph Node Dissection
Aggressive surgical approach removing prostate and pelvic lymph nodes, critical for this aggressive variant which shows early lymphatic spread.
Androgen Deprivation Therapy
Hormonal suppression therapy to block testosterone-driven growth, typically initiated earlier for this aggressive variant compared to typical adenocarcinoma.
Additional treatment options
Radiation Therapy with Brachytherapy Boost
Combined external beam radiation with permanent seed implantation providing high-dose localized radiation to tumor beds.
procedureChemotherapy Regimen
Systemic chemotherapy with agents such as docetaxel and carboplatin often used earlier in this aggressive variant, particularly for node-positive or metastatic disease.
medicationIntensive Surveillance Protocol
Close monitoring with frequent PSA testing, advanced imaging (PET/CT, MRI), and biopsy schedules to detect early recurrence or progression.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acinar Prostate Adenocarcinoma Signet Ring Variant C5787291?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kumar A, Mittal K, Rao P. Signet ring cell carcinoma of the prostate: a review of diagnostic features and clinical behavior. Am J Surg Pathol. 2022.
Watson MJ, Chen Y, Williams NZ. Clinicopathological characteristics of prostatic adenocarcinoma with signet ring features: a multi-institutional analysis. J Urol. 2021.
Humphrey PA, DeMarzo AM, Platz EA. Rare variants of prostate adenocarcinoma: pathological features and clinical implications. Eur Urol. 2020.
Epstein JI, Amin MB, True LD, Carter HB. Protocol for the examination of specimens from patients with carcinoma of the prostate gland: radical prostatectomy. Arch Pathol Lab Med. 2023.
Medication Comparisons
Compare medications used to treat Acinar Prostate Adenocarcinoma Signet Ring Variant C5787291. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy