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Acquired Susceptibility To Long Qt Syndrome 1 C1843738

Published: July 22, 2026Updated: August 26, 2026

A heart rhythm problem where certain medicines or conditions cause dangerously long pauses between beats. Affected people must avoid specific drugs and be monitored.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

ICD-10
I45.81
ICD-11
BA00.0
Body system
cardiovascular
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Syncope

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Palpitations

!

Chest discomfort

Chest discomfort or palpitations

(cardiovascular)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Dizziness

(cardiovascular)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Beta-Adrenergic Blockers

Beta-blockers are the primary pharmacological intervention for acquired long QT syndrome, reducing cardiac events by decreasing sympathetic drive and preventing stress-triggered arrhythmias.

medication
2

Disease management and monitoring

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Strenuous Exercise Avoidance

Avoidance of competitive sports, intense physical exertion, and swimming alone is essential, as exercise and emotional stress are common triggers for dangerous arrhythmias in susceptible individuals.

lifestyle

Additional treatment options

Sodium Channel Blockers

Medications such as flecainide or mexiletine may be considered as adjunctive therapy in select patients to reduce arrhythmia burden, though their use requires careful monitoring and expertise.

medication

Left Cardiac Sympathetic Denervation

Surgical removal of the left stellate ganglion reduces sympathetic innervation to the heart, significantly decreasing arrhythmia risk in patients who fail medical management.

surgical

Implantable Loop Recorder Monitoring

Continuous rhythm monitoring with an implantable device allows detection of asymptomatic arrhythmias and helps guide therapy adjustments in high-risk patients.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acquired Susceptibility To Long Qt Syndrome 1 C1843738?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Priori SG, Blomström-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2015;36(41):2793-2867.

guideline2015
2

Yap YG, Camm AJ. Drug induced QT prolongation and torsades de pointes. Heart. 2003;89(11):1363-1372.

review2003
3

Roden DM. Long QT syndrome: reduced repolarization reserve and the genetic link. J Clin Invest. 2006;116(10):2597-2600.

review2006
4

Moss AJ, Zareba W, Hall WJ, et al. Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome. Circulation. 2000;101(6):616-623.

clinical_trial2000

Medication Comparisons

Compare medications used to treat Acquired Susceptibility To Long Qt Syndrome 1 C1843738. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy