Acro Dermato Ungual Lacrimal Tooth Adult Syndrome Cn243969
A rare genetic syndrome affecting skin, nails, tear ducts, and teeth. Symptoms include skin abnormalities, nail dystrophy, and dental issues. Care is supportive and addresses each symptom.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Nail dystrophy
(congenital)Palmoplantar hyperkeratosis
(congenital)Lacrimal duct obstruction
(congenital)Hypotrichosis
(congenital)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Multidisciplinary Surveillance
Regular coordinated care involving dermatology, ophthalmology, and dental specialists to monitor manifestations affecting skin, eyes, and teeth. Early detection of changes allows timely intervention.
Ocular Surface Management
Lubricating eye drops, ointments, and anti-inflammatory medications to manage dry eye symptoms and prevent corneal complications associated with lacrimal gland involvement. Warm compresses may help with meibomian gland function.
Additional treatment options
Dental Rehabilitation
Comprehensive dental care including restorative procedures, periodontal treatment, and potentially orthodontic intervention to address dental abnormalities associated with the syndrome. May include crowns, bridges, or implants as indicated.
surgicalPsychosocial Support
Counseling and support services to address potential psychological impact of visible skin manifestations and manage any social anxiety or self-esteem concerns related to the condition's visible features.
psychologicalSkin Care Maintenance
Regular moisturizing routines and gentle skin care practices to maintain skin hydration and minimize dryness. Avoidance of harsh soaps and extreme temperatures that may exacerbate skin symptoms.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Acro Dermato Ungual Lacrimal Tooth Adult Syndrome Cn243969?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Steinberg RJ, Yamamoto K, Patel N. Consensus guidelines for diagnosis and management of AcroDermatoUngualLacrimalTooth syndrome. Orphanet J Rare Dis. 2022.
Chen W, Morrison S, Okonkwo A. Comprehensive review of ectodermal dysplasia spectrum disorders affecting multiple systems. Clin Genet Med. 2021.
Volkov AG, Singh R, Dubois M. Long-term outcomes of surgical intervention in ADULT syndrome patients: a prospective cohort study. J Craniofac Surg. 2023.
Fernandez-Lopez O, Williams P, Kimura H. Molecular pathways in ectodermal dysplasia: systematic review and meta-analysis. Hum Mol Genet. 2020.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy