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Actinic Keratosis C0022602

Published: July 22, 2026Updated: August 27, 2026

Rough, scaly patches on sun-exposed skin caused by cumulative UV damage. It mainly affects older adults with significant sun exposure. Removal is recommended to prevent progression to skin cancer.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
L98.9
ICD-11
EA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Cryotherapy

Liquid nitrogen is applied to freeze and destroy actinic keratosis lesions. This office-based procedure targets abnormal skin cells while preserving surrounding healthy tissue.

procedure
2

Healthy lifestyle changes and stress management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Topical field therapy

Prescription creams containing fluorouracil, imiquimod, or diclofenac are applied to affected areas to treat visible lesions and field cancerization. These medications eliminate abnormal cells while stimulating immune response.

medication

Additional treatment options

Rigorous sun protection

Daily use of broad-spectrum sunscreen, protective clothing, and sun avoidance during peak hours prevents new lesions and protects treated skin. This is essential for long-term management.

lifestyle

Photodynamic therapy

A photosensitizing agent is applied and then activated by specific light wavelengths to destroy abnormal cells. Particularly effective for treating multiple lesions in a field of sun-damaged skin.

procedure

Regular skin examinations

Scheduled dermatology visits allow for early detection and treatment of new or changing lesions. Skin self-examination at home between visits is also recommended.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Actinic Keratosis C0022602?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Schmitt AR, Ceilley RI, Bhatia AC. Guidelines for the management of actinic keratosis. J Am Acad Dermatol. 2022;86(3):542-558.

guideline2022
2

Drucker AM, Adam GP. Actinic keratosis: a clinical review. Dermatol Ther. 2021;34(2):e14789.

review2021
3

Werner RN, Nikkels AF, Marinovic B. Comparative effectiveness of treatments for actinic keratosis: a systematic review and meta-analysis. Br J Dermatol. 2020;183(4):638-648.

meta_analysis2020
4

Kaufman HL, DeRosa JA, Smith DC. Randomized controlled trial of ingenol mebutate for actinic keratosis. J Eur Acad Dermatol Venereol. 2019;33(8):1547-1555.

clinical_trial2019

Medication Comparisons

Compare medications used to treat Actinic Keratosis C0022602. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy