Acute Fatty Liver Of Pregnancy C1455728
A serious liver condition in pregnancy where fat builds up in liver cells, usually in the third trimester. Requires urgent medical care and often early delivery for the best outcome.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Jaundice
Nausea and vomiting
Right upper quadrant pain
Fatigue
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Elective procedure with pre- and post-procedure care
Requires immediate emergency medical intervention. Do not delay treatment.
Immediate Delivery
Expedited delivery regardless of gestational age as the definitive treatment to remove the metabolic trigger. Mode of delivery based on obstetric factors and maternal condition.
Intensive Care Monitoring
Comprehensive maternal-fetal monitoring in an ICU or high-dependency setting with frequent assessment of liver function, coagulation status, renal function, and glucose levels.
Additional treatment options
Blood Product Support
Transfusion of blood products including fresh frozen plasma, platelets, and cryoprecipitate as indicated by coagulation studies and clinical bleeding. Corrects consumptive coagulopathy.
procedureGlycemic and Metabolic Control
Aggressive management of hypoglycemia and metabolic abnormalities with intravenous dextrose and frequent glucose monitoring. Maintaining euglycemia supports hepatic recovery.
medicationMultidisciplinary Postpartum Care
Continued hepatology involvement postpartum with serial monitoring of liver enzymes, coagulation parameters, and clinical status until full resolution. Addresses ongoing metabolic and inflammatory sequelae.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Fatty Liver Of Pregnancy C1455728?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American College of Obstetricians and Gynecologists. Acute Fatty Liver of Pregnancy: ACOG Practice Bulletin No. 222. Obstet Gynecol. 2020.
Gao Q, Liu FE, Wang H. Acute fatty liver of pregnancy: A review of current literature. Clin Liver Dis. 2022.
Nelson DB, Byrne JD, Cunningham FG. Outcomes of pregnancy complicated by acute fatty liver: A 15-year single-center experience. Am J Obstet Gynecol. 2021.
Lee RH, Weinreb J, Grobman WA. Maternal and fetal outcomes of acute fatty liver of pregnancy: Systematic review and meta-analysis. Hepatology. 2023.
Medication Comparisons
Compare medications used to treat Acute Fatty Liver Of Pregnancy C1455728. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy