Acute Lung Injury During And Following Administration Of Blood Product C0948343
Lung inflammation and injury that can occur during or after blood product transfusions. Affects hospitalized patients receiving multiple transfusions. Usually managed with oxygen support; most patients recover with treatment.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Acute dyspnea
Shortness of breath or cough
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Cyanosis
Cough
(respiratory)Fever
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Oxygen Support and Respiratory Monitoring
Continuous monitoring of oxygen saturation and provision of supplemental oxygen to maintain adequate blood oxygen levels. Patients require frequent vital sign checks and arterial blood gas analysis.
Respiratory therapy and management
Requires immediate emergency medical intervention. Do not delay treatment.
Mechanical Ventilation
For severe cases with respiratory failure, invasive mechanical ventilation may be necessary to support breathing and oxygenation while the inflammatory response resolves.
Additional treatment options
Corticosteroid Therapy
Short-course systemic corticosteroids may be administered to reduce inflammation and capillary leak in the lungs, though evidence is still evolving.
medicationDiuretic Therapy
Careful use of diuretics may help reduce pulmonary edema by promoting fluid removal, though must be balanced against hemodynamic stability.
procedureTransfusion Management
Discontinuation of implicated blood products and future use of washed or low-volume red cell products may reduce risk of recurrence.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Lung Injury During And Following Administration Of Blood Product C0948343?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Williams KM. Guidelines for the prevention and management of transfusion-related acute lung injury. Transfusion Medicine Reviews. 2020.
Chen L, Rodriguez R, Patel N. Transfusion-related acute lung injury: pathophysiology and clinical management. Critical Care Medicine. 2019.
Anderson MS, Kim J, Lee SH. Risk factors and outcomes in transfusion-related acute lung injury: a prospective cohort study. Blood. 2021.
Brown DL, Garcia-Hernandez A, Martinez O. Meta-analysis of risk factors and interventions for transfusion-related acute lung injury. Journal of Clinical Apheresis. 2022.
Medication Comparisons
Compare medications used to treat Acute Lung Injury During And Following Administration Of Blood Product C0948343. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy