Acute Myeloid Leukemia Del 5q31 Q32 Cn305559
A blood cancer marked by deletion of part of chromosome 5. This chromosomal abnormality is often associated with a less favorable outlook. Treatment usually involves intensive chemotherapy.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Severe headache
Fatigue
(hematologic)Easy bruising
(hematologic)Frequent infections
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hypomethylating Agent Therapy
Azacitidine or decitabine-based therapy targeting abnormal DNA methylation patterns in leukemic cells, offering a lower-intensity option for older or less fit patients.
Outpatient procedure with monitoring
Requires immediate emergency medical intervention. Do not delay treatment.
Intensive Chemotherapy
Standard "7+3" cytarabine and anthracycline induction therapy targeting rapid cytoreduction in patients who are medically fit for aggressive treatment.
Additional treatment options
Allogeneic Stem Cell Transplant
Definitive curative approach using donor stem cells to establish new hematopoiesis after myeloablative conditioning, particularly important for high-risk cytogenetics.
procedureSerial Cytogenetic Monitoring
Regular bone marrow assessments to track chromosomal abnormalities and detect minimal residual disease, guiding treatment decisions and transplant timing.
monitoringActivity Modification and Infection Prevention
Patient education on avoiding crowds, hand hygiene, food safety practices, and energy conservation techniques during immunocompromised periods.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia Del 5q31 Q32 Cn305559?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Acute Myeloid Leukemia. Version 3.2023. NCCN Guidelines. 2023.
Kumar CC, Patel MM. Cytogenetic Abnormalities in Acute Myeloid Leukemia: Focus on Chromosome 5q Deletions. Blood Rev. 2021;35:100732.
Zhang R, Lee SM, Chen J, et al. Targeted Therapy for Acute Myeloid Leukemia with Deletion 5q31-q32: A Phase II Clinical Trial. J Clin Oncol. 2022;40(15_suppl):7012.
Schiffer CA, Davis H, Thompson AA. Prognostic Significance of Chromosomal Abnormalities in Adult Acute Myeloid Leukemia. Leuk Lymphoma. 2020;61(8):1848-1861.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia Del 5q31 Q32 Cn305559. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy