Acute Myeloid Leukemia M6 Type C0023440
AML M6 type, or acute erythroid leukemia, involves abnormal proliferation of red blood cell precursors. It's a rare subtype. Treatment includes chemotherapy and possibly transplant.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Bleeding gums
Fatigue
(hematologic)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Pallor
(hematologic)Bone pain
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High-Dose Cytarabine-Based Induction
Intensive chemotherapy regimen specifically targeting acute megakaryoblastic leukemia (M6), which often shows resistance to standard regimens. Cytarabine at high doses may overcome drug resistance mechanisms.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Allogeneic Stem Cell Transplantation
Potentially curative procedure involving donor stem cell infusion after myeloablative conditioning. Particularly important in M6 AML due to higher relapse rates with chemotherapy alone.
Additional treatment options
Gemtuzumab Ozogamicin
Antibody-drug conjugate targeting CD33 antigen, which may be expressed in M6 AML. Provides targeted delivery of cytotoxic agent directly to leukemia cells.
medicationSupportive Transfusion Care
Regular platelet and red blood cell transfusions to manage cytopenias during intensive treatment phases. Includes irradiated blood products to prevent graft-versus-host reactions.
complementaryNutritional Support Program
Specialized nutritional intervention including high-calorie supplements and appetite stimulants to prevent treatment-related malnutrition and cachexia common in M6 AML.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia M6 Type C0023440?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Döhner H, Estey EH, Amadori S. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel. Blood. 2017.
Khwaja A, Bjorkholm M, Gale RE. Acute myeloid leukaemia. Nat Rev Dis Primers. 2016.
Wei AH, Tiong IS, Sill H. Safety and efficacy of venetoclax plus low-dose cytarabine in previously untreated patients with acute myeloid leukemia: Results from a phase 1b/2 study. J Clin Oncol. 2020.
Wang ES, Dinardo CD, Kadia TM. Impact of Consolidation Therapy in Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis. Haematologica. 2021.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia M6 Type C0023440. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy