Acute Myeloid Leukemia T 3 3 Q21 3 Q26 2 Cn305557
A blood cancer that starts in the bone marrow where abnormal cells crowd out healthy ones. More common in older adults. Treatment may include intensive chemotherapy and transplant.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe headache
Fatigue
(general)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Bleeding or easy bruising
(hematologic)Fever and infection
(general)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hypomethylating Agent Therapy
Use of azacitidine or decitabine to modify gene expression patterns in leukemic cells, particularly relevant for high-risk AML with EVI1 overexpression.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Reduced-Intensity Stem Cell Transplant
Modified transplant conditioning regimen suitable for patients who cannot tolerate standard transplant due to age or comorbidities, while still providing graft-versus-leukemia effect.
Additional treatment options
Supportive Care with Growth Factors
Granulocyte colony-stimulating factor support to accelerate neutrophil recovery and reduce infection risk during treatment phases.
medicationIntensive Infection Surveillance
Regular monitoring for bacterial, fungal, and viral infections with prophylactic antimicrobials and prompt diagnostic workup of febrile episodes.
monitoringIntegrative Medicine Support
Acupuncture and mindfulness-based stress reduction to manage treatment side effects including nausea, pain, and chemotherapy-induced neuropathy.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia T 3 3 Q21 3 Q26 2 Cn305557?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Döhner H, Estey E, Grimwade D, et al. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017.
Grossmann V, Schnittger S, Schindela S, et al. The molecular portrait of acute myeloid leukemia with inv(3)/t(3;3) identifies MECOM overexpression as a characteristic feature. Haematologica. 2012.
Lugten PJ, Beverloo HB, Valk PJ, et al. Acute myeloid leukemia with t(3;3)(q21;q26) is characterized by a distinct biological and clinical profile. Leukemia. 2015.
Kayser S, Zucknick M, Döhner K, et al. Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome in 4239 patients. J Clin Oncol. 2014.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia T 3 3 Q21 3 Q26 2 Cn305557. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy