Acute Myeloid Leukemia With Abnormal Bone Marrow Eosinophils Inv 16 P13q22 Or T 16 16 P13 Q22 C5395080
A specific subtype of acute myeloid leukemia with a chromosomal abnormality called inv(16) or t(16;16), affecting bone marrow eosinophils. It typically occurs in adults and often involves abnormal white blood cells called eosinophils. This subtype generally has a more favorable response to treatment.
Key facts at a glance
- ICD-10
- C96.9
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Fatigue
(hematologic)Fever
(hematologic)Easy bruising
(hematologic)Bone pain
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High-Dose Cytarabine Consolidation
Multi-cycle cytarabine-based consolidation chemotherapy following induction remission, leveraging the excellent response rate in this AML subtype.
Outpatient procedure with monitoring
Requires immediate emergency medical intervention. Do not delay treatment.
Induction Chemotherapy Regimen
Combined anthracycline and cytarabine chemotherapy to achieve first complete remission in newly diagnosed patients.
Additional treatment options
Autologous Stem Cell Transplant
Collection and reinfusion of patient's own stem cells following high-dose chemotherapy for eligible patients in remission.
procedureBone Marrow Response Assessment
Regular morphologic, immunophenotypic, and molecular monitoring to assess treatment response and detect early relapse.
monitoringNutritional Support Program
Enteral or parenteral nutrition support to maintain nutritional status during intensive treatment phases when oral intake is inadequate.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia With Abnormal Bone Marrow Eosinophils Inv 16 P13q22 Or T 16 16 P13 Q22 C5395080?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Arber DA, Orazi A, Hasserjian RP, et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemia. Blood. 2022.
Döhner H, Weisdorf DJ, Bloomfield CD. Acute Myeloid Leukemia. N Engl J Med. 2022.
Feng S, Zhou J, Wang D, et al. Venetoclax and Azacitidine in Newly Diagnosed Acute Myeloid Leukemia With inv(16). J Clin Oncol. 2023.
Byrd JC, Mrozek K, Dodge RK, et al. Pretreatment Cytogenetic Abnormalities Are Predictive of Induction Success, Cumulative Incidence of Relapse, and Overall Survival in Adult Patients With de Novo Acute Myeloid Leukemia: Results From Cancer and Leukemia Group B (CALGB 8461). Blood. 2012.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia With Abnormal Bone Marrow Eosinophils Inv 16 P13q22 Or T 16 16 P13 Q22 C5395080. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy