Acute Myeloid Leukemia With Multilineage Dysplasia C1292773
An acute myeloid leukemia characterized by abnormal development in multiple blood cell lines. It is more common in older adults and may arise from prior blood disorders. Treatment outcomes vary, with some cases being more resistant to therapy.
Key facts at a glance
- ICD-10
- C92.A0, C92.A1, C92.A2
- ICD-11
- 2A00.0
- Body system
- hematologic
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Severe headache
Fatigue
(hematologic)Easy bruising or bleeding
(hematologic)Bone pain
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hypomethylating Agent Therapy
Use of demethylating agents to modify gene expression patterns in dysplastic cells, often combined with other agents to improve response rates.
Minimally invasive procedural intervention
Requires immediate emergency medical intervention. Do not delay treatment.
Allogeneic Stem Cell Transplant
Curative-intent transplant approach using donor stem cells to replace the abnormal bone marrow environment contributing to dysplasia.
Additional treatment options
Low-Dose Chemotherapy
Less intensive chemotherapy approach using lower doses of cytotoxic agents to achieve disease control while minimizing toxicity in frail patients.
medicationBone Marrow Response Assessment
Serial bone marrow biopsies to evaluate morphologic and cytogenetic response, guiding treatment continuation or modification.
monitoringNutritional Support Therapy
Specialized dietary interventions to address malnutrition and support immune function during intensive treatment periods.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Acute Myeloid Leukemia With Multilineage Dysplasia C1292773?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Arber DA, Orazi A, Hasserjian RP, et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemia. Blood. 2022.
Döhner H, Wei AH, Appelbaum FR, et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel. Blood. 2022.
Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2017.
Miesner M, Haferlach C, Bacher U, et al. Multilineage dysplasia in acute myeloid leukemia: impact on prognosis and clinical significance. Haematologica. 2010.
Medication Comparisons
Compare medications used to treat Acute Myeloid Leukemia With Multilineage Dysplasia C1292773. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy