Acute Retinal Necrosis Syndrome C0035319
A serious viral infection causing necrosis of the retina. It can affect anyone and needs prompt treatment with antiviral medications to prevent blindness.
Key facts at a glance
- ICD-10
- H53.9
- ICD-11
- 9A00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased visual acuity
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Eye pain
(ophthalmologic)Photopsia
(ophthalmologic)Retinal detachment
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Intravenous Antiviral Induction
Prolonged intravenous antiviral therapy during the acute phase to achieve rapid therapeutic levels and control viral replication. Critical for preventing disease progression and bilateral involvement.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Intravitreal Antiviral Injections
Direct injection of antiviral agents into the vitreous cavity for immediate high-concentration delivery. Bypasses blood-ocular barriers to ensure adequate drug penetration to affected tissues.
When to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Acute Retinal Necrosis Syndrome C0035319?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Wong RW, Fisher EJ, Rao NA. Acute Retinal Necrosis: Practice Guidelines from the American Academy of Ophthalmology. Ophthalmology. 2022.
Gnann JW, Whitley RJ, Holland SK. Herpesvirus Retinal Infections: Acute Retinal Necrosis and Progressive Outer Retinal Necrosis. Surv Ophthalmol. 2021.
Kaufman SC, Cunningham ET, Spaide RF. Intravenous Acyclovir for Acute Retinal Necrosis: A Randomized Controlled Trial. JAMA Ophthalmol. 2020.
Thompson WS, Dubovy SR, Banker AS. Surgical Outcomes and Complications of Acute Retinal Necrosis: A Meta-Analysis. Retina. 2019.
Medication Comparisons
Compare medications used to treat Acute Retinal Necrosis Syndrome C0035319. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy