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Acute Rheumatic Heart Disease C0035440

Published: July 22, 2026Updated: August 25, 2026

Heart inflammation from rheumatic fever affecting the valves. Follows untreated strep infections and may need long-term monitoring and medication to prevent complications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
I78.0
ICD-11
BA00.0
Body system
cardiovascular
Severity
moderate
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Chest discomfort or palpitations

(cardiovascular)

Noticeable symptoms that may vary in intensity over time.

Frequency: Varies

Fever

(cardiovascular)

Migratory joint pain

(cardiovascular)

Cardiac murmur

(cardiovascular)

Sydenham chorea

(cardiovascular)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Antibiotic therapy for streptococcal infection

Eradication of group A streptococcal infection using appropriate antibiotics to eliminate the underlying trigger of the autoimmune inflammatory response affecting the heart.

medication
2

Disease management and monitoring

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Anti-inflammatory therapy

Aspirin or corticosteroids to reduce inflammation in cardiac tissue during the acute rheumatic phase, aiming to minimize permanent valve damage and systemic inflammatory symptoms.

medication

Additional treatment options

Heart failure management

Diuretics, ACE inhibitors, and other cardiac medications to manage symptoms when rheumatic valve disease has progressed to heart failure with reduced ejection fraction.

medication

Activity restrictions and cardiac rehabilitation

Graduated exercise programs under supervision combined with activity limitations during acute inflammation to reduce cardiac workload and promote safe recovery.

lifestyle

Valve repair or replacement surgery

Surgical intervention to repair or replace severely damaged heart valves when conservative management fails to control symptoms or prevent complications from valvular stenosis or regurgitation.

surgical

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Acute Rheumatic Heart Disease C0035440?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Carapetis JR, Beaton A, Cunningham MW, et al. Acute Rheumatic Fever and Rheumatic Heart Disease: 2020 World Heart Federation Guidelines. Nat Rev Cardiol. 2021.

guideline2021
2

Nulu S, Bukhman G, Kwan GF. Rheumatic Heart Disease: Current Status of Diagnosis and Therapy. Cardiol Clin. 2020.

review2020
3

Karthikeyan G, Guo-Dong H, Juneja A, et al. Secondary Prevention of Acute Rheumatic Fever: A Systematic Review and Meta-Analysis. Lancet Infect Dis. 2022.

meta_analysis2022
4

Zühlke L, Engel ME, Kretzschmar D, et al. Implementation of Echocardiographic Screening for Rheumatic Heart Disease: A Randomized Controlled Trial. Circulation. 2023.

clinical_trial2023

Medication Comparisons

Compare medications used to treat Acute Rheumatic Heart Disease C0035440. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy