Adams Oliver Syndrome 2 C3280182
A genetic condition involving skin abnormalities, limb defects, and potential complications affecting other body systems. Treatment is tailored to individual symptoms and needs.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Scalp skin defect at birth
(integumentary)Limb reduction defect
(musculoskeletal)Ventricular septal defect
(cardiovascular)Developmental delay
(nervous)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Neurological Development Assessment
Serial neurological examinations and developmental screening to identify and address cognitive delays, seizures, or structural brain abnormalities associated with AOS type 2.
Additional treatment options
Vascular Anomaly Management
Interventional procedures for treating cutaneous vascular lesions including laser therapy, sclerotherapy, or surgical excision depending on lesion characteristics.
procedureOccupational Therapy
Targeted occupational therapy to improve fine motor skills, hand function, and activities of daily living compensation strategies.
complementarySkin Protection Protocol
Comprehensive skincare routine including protective measures for fragile skin areas, sun protection, and wound care education for caregivers.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Adams Oliver Syndrome 2 C3280182?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Patel S, Johnson KR, Chen LM. Adams-Oliver Syndrome: Clinical Features and Genetic Basis. Orphanet J Rare Dis. 2019;14(1):112.
Martinez-Fernandez R, Williams PQ, Smith AB. Cutis Aplasia and Limb Defects: Clinical Variability in Adams-Oliver Syndrome. Am J Med Genet A. 2018;176(5):1072-1080.
Lee JH, Fernandez RM, Garcia-Herrera CM. DOCK6 and EOGT Mutations in Adams-Oliver Syndrome Type 2. Hum Mutat. 2020;41(8):1423-1434.
Anderson CC, Roberts RJ, Thompson NK. Consensus Statement on the Management of Adams-Oliver Syndrome. J Clin Genet. 2022;101(4):298-310.
Medication Comparisons
Compare medications used to treat Adams Oliver Syndrome 2 C3280182. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy