Adenocarcinoma Of The Liver And Intrahepatic Biliary Tract C5192429
A cancer that forms in the liver or bile ducts inside the liver. Treatment options may include surgery, ablation, chemotherapy, or liver transplantation.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain
(hepatobiliary)Generalized symptoms
(hepatobiliary)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Weight loss
(hepatobiliary)Hepatomegaly
(hepatobiliary)Ascites
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Resection
Complete surgical removal of the tumor and surrounding liver tissue when feasible. This is the potentially curative approach for localized disease, requiring careful evaluation of tumor size, location, and liver function reserve.
Additional treatment options
Transarterial Chemoembolization (TACE)
A minimally invasive procedure that delivers chemotherapy directly to the tumor while blocking its blood supply. This approach is particularly beneficial for patients with intermediate-stage disease or those unsuitable for surgery.
procedureSystemic Chemotherapy
Combination chemotherapy regimens targeting rapidly dividing cancer cells. Typically used for advanced or metastatic disease to slow progression and manage symptoms.
medicationTargeted Therapy
Molecularly targeted agents such as tyrosine kinase inhibitors that interfere with specific pathways driving tumor growth. These medications are used in advanced biliary tract cancers.
medicationSurveillance and Supportive Care
Regular imaging and tumor marker monitoring to track disease progression and treatment response. Includes nutritional support, pain management, and palliative care integration.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adenocarcinoma Of The Liver And Intrahepatic Biliary Tract C5192429?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Benson AB, D'Angelica MI, Abrams TA. Hepatobiliary Cancers, Version 2.2023. J Natl Compr Canc Netw. 2023.
Kelley RK, Gordan JD, Ko AH, et al. Systemic therapy for advanced hepatocellular carcinoma and biliary tract cancers. J Clin Oncol. 2022.
Finn RS, Qin S, Ikeda M, et al. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med. 2020.
Yarchoan M, Agarwal P, Villanueva A, et al. Recent developments and therapeutic strategies against hepatocellular carcinoma. Cancer Res. 2019.
Medication Comparisons
Compare medications used to treat Adenocarcinoma Of The Liver And Intrahepatic Biliary Tract C5192429. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy