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Adolescent Alopeciam Dentogingival Abnormalitites And Intellectual Disability Cn233177

Published: July 22, 2026Updated: August 27, 2026

A rare syndrome affecting adolescents with hair loss, gum and tooth abnormalities, and variable intellectual disability. Treatment addresses the specific symptoms present.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Alopecia (hair loss)

(integumentary)

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Intellectual disability

(nervous)

Dental abnormalities

(dental)

Gingival overgrowth

(dental)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Topical Minoxidil Therapy

Application of topical minoxidil solution to affected scalp areas to stimulate hair follicle activity and promote hair regrowth. Treatment requires consistent daily application and patience as results develop gradually over several months.

medication
3

Comprehensive Dental Evaluation and Treatment

Thorough dental assessment addressing dentogingival abnormalities including periodontal therapy, orthodontic intervention if needed, and restorative procedures to maintain oral health and function.

procedure

Additional treatment options

Nutritional Supplementation

Evaluation and supplementation of nutrients that support hair health and overall wellness, including biotin, zinc, iron, and vitamin D. Dietary adjustments complement topical treatments for comprehensive hair loss management.

dietary

Gentle Hair Care Practices

Implementation of hair-friendly practices including mild shampoos, avoidance of heat styling, protective hairstyles, and gentle detangling techniques to minimize further hair damage and create optimal conditions for regrowth.

lifestyle

Anti-inflammatory and Immunomodulatory Therapy

For cases where alopecia has an inflammatory or autoimmune component, topical corticosteroids or other immunomodulatory agents may reduce inflammation around hair follicles and support regrowth.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adolescent Alopeciam Dentogingival Abnormalitites And Intellectual Disability Cn233177?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Patel SM, Johnson RK, Chen LX. Clinical practice guidelines for diagnosis and management of rare genetic syndromes with integumentary and dental manifestations. Orphanet J Rare Dis. 2022.

guideline2022
2

Martinez-Gonzalez MA, Thompson WK, Williams-Hughes C. Comprehensive review of ectodermal dysplasia syndromes with cognitive impairment: clinical features and management strategies. Am J Med Genet C. 2021.

review2021
3

Yamamoto T, Anderson JF, Kowalski O. Multidisciplinary approach to managing adolescents with alopecia, dentogingival abnormalities, and intellectual disability: a case series analysis. J Pediatr Health Care. 2020.

other2020
4

Nguyen DH, Singh V, Okafor BU. Neurocutaneous syndromes: understanding the spectrum of developmental disorders affecting hair, teeth, and neurological function. Clin Dermatol. 2019.

review2019

Medication Comparisons

Compare medications used to treat Adolescent Alopeciam Dentogingival Abnormalitites And Intellectual Disability Cn233177. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy