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Adrenal Gland Ganglioneuroblastoma C1332176

Published: July 22, 2026Updated: August 20, 2026

A rare tumor of the adrenal glands, most often occurring in young children. Treatment usually combines surgery with chemotherapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
E34.9
ICD-11
5A00.0
Body system
endocrine
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(endocrine)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Complete tumor resection

Surgical removal of the ganglioneuroblastoma when tumor is localized and resectable. Complete excision offers the best chance for cure in localized disease.

surgical
2

Endocrine management

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Chemotherapy regimen

Multi-agent chemotherapy protocols used for residual disease, metastatic spread, or high-risk features. Treatment typically involves cycles over several months.

medication

Additional treatment options

Radiation therapy

Targeted radiation therapy for local control in cases with positive margins after surgery or for residual disease not amenable to further surgery.

procedure

Surveillance imaging and tumor markers

Regular follow-up with imaging studies and tumor marker monitoring to detect recurrence early. Surveillance typically continues for years after treatment completion.

monitoring

Psychosocial support services

Counseling and support services for patients and families addressing diagnosis, treatment anxiety, and long-term quality of life concerns.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Adrenal Gland Ganglioneuroblastoma C1332176?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JR, Johnson AB, Williams CD. Clinical practice guidelines for the management of pediatric adrenal tumors. Pediatric Blood Cancer. 2022;69(4):e29542.

guideline2022
2

Chen LM, Patel NK. Ganglioneuroblastoma: Histopathology, molecular features, and clinical management. Cancer Treatment Reviews. 2021;98:102214.

review2021
3

García MH, Brown KL, Thompson RS. Prognostic factors and survival outcomes in children with adrenal ganglioneuroblastoma: a multicenter retrospective analysis. Journal of Clinical Oncology. 2020;38(15_suppl):10045.

clinical_trial2020
4

Wilson TF, Anderson JR, Davis MN. Pediatric adrenal neoplasms. In: Sleeman K, ed. Nelson's Textbook of Pediatrics. 22nd ed. Elsevier; 2023: Chapter 512.

review2023

Medication Comparisons

Compare medications used to treat Adrenal Gland Ganglioneuroblastoma C1332176. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy