Adult Infiltrating Astrocytic Neoplasm C0281329
A type of brain tumor that develops from star-shaped brain cells called astrocytes. These tumors can vary in aggressiveness. Treatment often includes surgery, radiation, and chemotherapy, with outlook depending on the tumor grade and location.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Headache
Motor weakness
Visual disturbances
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Seizures
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Maximal Safe Surgical Resection
Surgical removal of the tumor with preservation of neurological function. Extent of resection is a critical prognostic factor for infiltrating astrocytic neoplasms.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Radiation Therapy
External beam radiation therapy targeting the tumor bed and surrounding margins. May be used adjuvantly after surgery or as primary treatment when resection is not feasible.
Additional treatment options
Chemotherapy
Systemic chemotherapy agents used in combination with radiation or as standalone treatment for progressive disease. May include alkylating agents or targeted therapies.
medicationSerial MRI Surveillance
Regular magnetic resonance imaging to monitor for tumor progression or recurrence. Imaging schedule is tailored based on tumor grade and treatment phase.
monitoringSupportive Care and Rehabilitation
Multidisciplinary supportive services including physical therapy, occupational therapy, and speech therapy to address neurological deficits and maintain quality of life.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Adult Infiltrating Astrocytic Neoplasm C0281329?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Weller M, van den Bent M, Tonn JC, et al. European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas. Neuro-Oncology. 2021.
Reuss DE, von Deimling A. Adult diffuse astrocytic glioma with IDH1/2 mutation. Virchows Arch. 2023.
Han S, Chen Y, Wang P, et al. Extent of resection in infiltrating astrocytomas and survival outcomes: A systematic review and meta-analysis. J Clin Neurosci. 2022.
Hegi ME, Diserens AC, Gorlia T, et al. Long-term outcome with temozolomide and radiation in newly diagnosed glioblastoma: A randomized phase III trial. Lancet Oncol. 2020.
Medication Comparisons
Compare medications used to treat Adult Infiltrating Astrocytic Neoplasm C0281329. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy