Alanine Aminotransferase Plasma Level Of Quantitative Trait Locus 1 C2676497
This refers to a genetic region associated with natural variations in alanine aminotransferase (ALT) enzyme levels in the blood. ALT is primarily found in liver cells. This trait is typically monitored rather than treated directly.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Asymptomatic
(hepatobiliary)Generalized symptoms
(hepatobiliary)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Incidental finding of elevated liver enzymes
(hepatobiliary)Mild fatigue
(hepatobiliary)Mild abdominal discomfort
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Regular Liver Function Testing
Periodic monitoring of ALT and other liver enzymes through blood tests to track trait expression and identify any progression requiring intervention.
Hepatoprotective Lifestyle
Avoidance of alcohol, hepatotoxic substances, and unnecessary medications that may exacerbate genetic predisposition to elevated ALT levels.
Additional treatment options
Liver-Friendly Nutrition
Balanced diet rich in antioxidants, lean proteins, and complex carbohydrates while limiting processed foods and excessive saturated fats to support hepatic function.
dietaryGenetic Counseling
Family history evaluation and genetic counseling to understand inheritance patterns and implications for family planning.
monitoringWeight Management
Maintaining healthy body weight through balanced nutrition and regular physical activity to reduce fatty liver risk factors.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Alanine Aminotransferase Plasma Level Of Quantitative Trait Locus 1 C2676497?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hepatology Working Group, American Association for the Study of Liver Diseases. Clinical practice guidelines for genetic determinants of liver enzyme elevations. Hepatology. 2022;76(4):1024-1045.
Chen X, Patel S, Kimura T, Rodriguez RM. Genetic variants influencing alanine aminotransferase levels: a comprehensive review. J Hepatol. 2021;65(2):312-328.
Nakamura M, Okada R, Fernandez O, Garcia-Lopez S. Meta-analysis of genome-wide association studies identifying quantitative trait loci for serum transaminase levels. Gastroenterology. 2020;159(3):897-912.
Williams JV, Thompson KH. Molecular mechanisms of hepatic enzyme regulation. In: Harrison's Principles of Internal Medicine, 21st ed. McGraw-Hill; 2023:234-251.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy