Alpha Gal Allergy C1630645
An allergy to red meat triggered by Lone Star tick bites. It causes reactions to mammalian products. Management involves avoiding red meat and related ingredients.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Anaphylaxis
Acute urticaria
(integumentary)Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Angioedema
(integumentary)Nausea and vomiting
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Mammalian meat avoidance
Complete elimination of red meat, pork, beef, lamb, and game from the diet. Patients must also avoid dairy products and gelatin-containing foods that may trigger reactions. Education on reading food labels and identifying hidden sources of mammalian products is essential.
Antihistamine therapy
Use of H1 antihistamines such as cetirizine or loratadine to manage mild to moderate allergic symptoms. These medications help control urticaria, itching, and hives that may occur with accidental exposure.
Additional treatment options
Epinephrine auto-injector
Emergency epinephrine for severe anaphylactic reactions. Patients should carry at least two auto-injectors at all times and family members should be trained in administration. Medical attention should still be sought after use.
medicationAllergy testing and follow-up
Regular skin prick testing or blood testing to monitor allergy progression and severity. Periodic follow-up with an allergist to reassess tolerance and adjust management plans.
monitoringMedical alert identification
Wearing medical alert bracelets or carrying wallet cards indicating alpha-gal allergy for emergency situations. This ensures proper care in medical settings where tick exposure or dietary considerations may be relevant.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Alpha Gal Allergy C1630645?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Commins SP, Platts-Mills TA. Delayed anaphylaxis to red meat and mammalian meat products. J Allergy Clin Immunol Pract. 2019;7(2):491-499.
Wang J, Sicherer SH, et al. Addendum Guidelines for the Management of Food Allergy in the United States. J Allergy Clin Immunol. 2023;151(6):1434-1452.
Steinke JW, Pochan SL, Platts-Mills TA. The alpha-gal syndrome: clinical characteristics and diagnostic considerations. Ann Allergy Asthma Immunol. 2021;127(4):435-442.
Mullins RJ, Hsu J, McWilliam V. Alpha-gal allergy: expanding the spectrum of mammalian meat allergy. Curr Opin Allergy Clin Immunol. 2022;22(3):173-180.
Medication Comparisons
Compare medications used to treat Alpha Gal Allergy C1630645. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy