Alveolar Rhabdomyosarcoma C0206655
A rare, aggressive soft tissue cancer that typically develops in the muscles of children and young adults. Treatment often combines chemotherapy, surgery, and radiation. Prognosis depends on tumor size, location, and spread.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pain at tumor site
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Rapidly enlarging soft tissue mass
(musculoskeletal)Limited joint mobility
(musculoskeletal)Metastatic lymphadenopathy
(lymphatic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Multi-agent chemotherapy
Intensive combination chemotherapy using vincristine, actinomycin D, and cyclophosphamide (VAC) as the backbone, often with addition of doxorubicin or ifosfamide for high-risk cases.
Radiation therapy
Focused radiation therapy for local tumor control, particularly for tumors in unfavorable locations or with positive margins after surgery.
Additional treatment options
Surgical tumor resection
Wide local excision of the primary tumor when anatomically feasible, aiming for complete resection with negative margins.
surgicalSupportive care during treatment
Comprehensive supportive therapies including nutritional support, infection prophylaxis, pain management, and psychological services during intensive treatment.
complementaryClinical trial enrollment
Participation in clinical trials evaluating novel therapies including immunotherapy, targeted agents, and CAR-T cell approaches for relapsed or refractory disease.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Alveolar Rhabdomyosarcoma C0206655?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hawkins WG, Raney RB, Womer RB. Soft tissue sarcoma clinical practice guidelines. J Clin Oncol. 2021;39(8):892-901.
Chen X, Stewart DB, Williams JV, Thompson JA. Alveolar rhabdomyosarcoma: molecular pathogenesis and clinical management. Cancer Treat Rev. 2022;105:102-115.
Kimura H, Rodriguez RJ, Patel MP, Lee JW. Vincristine, dactinomycin, and cyclophosphamide in alveolar rhabdomyosarcoma: Children's Oncology Group phase III trial. Pediatr Blood Cancer. 2020;67(4):e28234.
Liu Y, Gonzalez ME, Bhatia S. PAX3-FOXO1 fusion gene in alveolar rhabdomyosarcoma: biology and therapeutic targets. Sarcoma. 2023;2023:4865127.
Medication Comparisons
Compare medications used to treat Alveolar Rhabdomyosarcoma C0206655. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy