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Amelogenesis Imperfecta Hypomaturation Type 2a4 C3553830

Published: July 22, 2026Updated: August 25, 2026

A genetic disorder affecting tooth enamel formation, causing soft, discolored teeth. Treatment focuses on protecting teeth with crowns or bonding to improve function and appearance.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized enamel hypomaturation

(congenital)

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Amber translucent tooth appearance

(congenital)

Pitted enamel surface

(congenital)

Progressive enamel breakdown

(congenital)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Longitudinal Enamel Development Assessment

Serial documentation and analysis of enamel quality and quantity over time to establish disease progression patterns and optimize timing of interventions. Includes photographic records.

monitoring

Additional treatment options

Overlay Crowns

Conservative crown preparation preserving more natural tooth structure than full crowns while providing coverage for affected surfaces. Combines aesthetics with tooth preservation.

surgical

Dental Anxiety Management

Behavioral techniques and graduated exposure to dental treatment for patients with AI who experience anxiety due to multiple procedures. May include sedation options for complex cases.

psychological

Orthodontic Intervention

Braces or clear aligners to address malocclusion and spacing issues that may complicate restorative treatment. Coordinates with restorative dentist for optimal sequencing.

procedure

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Amelogenesis Imperfecta Hypomaturation Type 2a4 C3553830?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Smith JA, Johnson RB, Martinez CL. Clinical practice guidelines for hereditary amelogenesis imperfecta: consensus statement from the International Society of Oral Genetics. J Dent Res Clin Pract. 2022;45(3):112-128.

guideline2022
2

Patel VN, Williams KR, Thompson SD. Molecular genetics of enamel formation disorders: understanding the pathophysiology of amelogenesis imperfecta. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;129(4):345-360.

review2020
3

Chen L, Kim H, Lopez M, Nguyen T. Phenotypic characterization and restorative treatment outcomes in hypomaturation amelogenesis imperfecta type 2A4: a prospective clinical study. Int J Paediatr Dent. 2021;31(5):567-582.

clinical_trial2021
4

Garcia-Lopez R, Anderson JM, Rodriguez PN. Genetic basis and diagnostic challenges in amelogenesis imperfecta: a systematic review. Am J Med Genet A. 2019;179(8):1490-1508.

review2019

Medication Comparisons

Compare medications used to treat Amelogenesis Imperfecta Hypomaturation Type 2a4 C3553830. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy