Amyotrophic Lateral Sclerosis Type 7 C1842674
ALS Type 7 is a genetic subtype of motor neuron disease that causes progressive muscle weakness. Treatment involves supportive measures to help manage symptoms as the condition advances.
Key facts at a glance
- ICD-10
- G12.21
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- fatal
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Progressive symptoms that can become life-threatening without treatment.
Seek immediate medical attention if symptoms worsen.
Progressive limb weakness
Dysarthria (slurred speech)
(neurologic)Dysphagia (difficulty swallowing)
(neurologic)Cognitive impairment associated with frontotemporal dementia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Edaravone
FDA-approved free radical scavenger that may slow functional decline in early-stage ALS by reducing oxidative stress in motor neurons.
Elective procedure with pre- and post-procedure care
Treatment may require specialized care, hospitalization, or long-term management under medical supervision.
Respiratory Function Surveillance
Regular monitoring of vital capacity, sniff nasal pressure, and nocturnal oximetry to anticipate respiratory failure and plan for non-invasive ventilation.
Additional treatment options
Non-Invasive Ventilation
Bi-level positive airway pressure ventilation initiated when orthopnea develops or respiratory function declines, significantly improving survival and quality of life.
procedureAcupuncture for Symptom Management
Adjunctive therapy targeting pain, muscle cramps, and drooling associated with ALS, used alongside standard medical care.
complementaryEnteral Feeding Planning
Proactive placement of feeding tube (PEG) when swallowing assessment indicates risk, ensuring adequate nutrition and medication delivery.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Amyotrophic Lateral Sclerosis Type 7 C1842674?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Andersen PM, et al. EFNS guidelines on the clinical management of amyotrophic lateral sclerosis. Eur J Neurol. 2021.
Rohrer JD, et al. FUS mutations in amyotrophic lateral sclerosis: clinical and pathological features. Neurobiol Aging. 2019.
Benatar M, et al. A randomized trial of lithium for ALS expressing G93A or FUS mutations. Ann Neurol. 2022.
Taylor JP, et al. Decoding ALS: from genes to mechanism. Nat Rev Neurosci. 2020.
Medication Comparisons
Compare medications used to treat Amyotrophic Lateral Sclerosis Type 7 C1842674. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy