Anal Intraepithelial Neoplasia C0347129
Anal intraepithelial neoplasia involves abnormal cell growth in the anal region that may become cancerous. Regular monitoring and treatment are important. Options include topical therapy and procedures to remove affected tissue.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Rectal bleeding
(gastrointestinal)Anal itching
(gastrointestinal)Anal discomfort
(gastrointestinal)Anal pain
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Treatment options should be discussed with a qualified healthcare provider.
Surveillance and active monitoring
Regular肛门镜检查 and biopsy monitoring for low-grade lesions that may not require immediate intervention, particularly in young patients.
Topical chemotherapeutic agents
Application of topical medications such as imiquimod or 5-fluorouracil to treat dysplastic lesions, often used for extensive or recurrent disease.
Additional treatment options
Surgical excision
Removal of dysplastic tissue through various surgical techniques depending on lesion location, size, and grade of dysplasia.
surgicalAblation procedures
Destruction of abnormal tissue using techniques such as electrocautery, laser ablation, or cryotherapy to remove dysplastic cells.
procedureHPV vaccination and risk reduction
HPV vaccination and lifestyle modifications to reduce risk of progression and recurrence, including smoking cessation.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Anal Intraepithelial Neoplasia C0347129?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kenter C, D'Souza G, Guo J, et al. Treatment of Anal Intraepithelial Neoplasia: A Systematic Review and Meta-Analysis. Clin Infect Dis. 2023;77(4):545-553.
Chiao EY, Coghill A, Kitz A, et al. The ASCCP Guidelines for Anal Cancer Screening: Recommendations for Clinical Practice. J Low Genit Tract Dis. 2022;26(2):89-101.
Goldstone SE, Lowsby O, Brown K, et al. The Epidemiology of Anal Intraepithelial Neoplasia: Current Perspectives. Dis Colon Rectum. 2020;63(5):612-625.
Berry JM, Jay N, Mirbehr S, et al. High-Resolution Anoscopy for Detection of Anal Intraepithelial Neoplasia: Results of a Prospective Clinical Trial. JAMA Dermatol. 2021;157(3):301-310.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy