Anaplastic Ganglioglioma C0431112
A rare brain tumor containing both nerve cell and glial cell components. Often occurs in younger patients and can be challenging to treat. Treatment typically involves surgery followed by chemotherapy or radiation.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
New-onset seizures
Focal neurological deficit
Persistent headache
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Cognitive decline
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Maximal Safe Resection
Aggressive surgical removal of the tumor while preserving neurological function. Extent of resection is strongly correlated with overall survival outcomes in anaplastic ganglioglioma.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Adjuvant Radiation Therapy
Fractionated stereotactic radiation delivered to the tumor bed and surrounding margins after surgery to eliminate residual tumor cells and reduce recurrence risk.
Additional treatment options
Chemotherapy
Systemic chemotherapy using agents such as temozolomide or nitrosoureas to target residual tumor cells. May be used adjunctively or for recurrent disease not amenable to further surgery.
medicationSerial MRI Imaging
Regular magnetic resonance imaging with contrast to monitor for tumor progression or recurrence. Imaging frequency typically decreases over time if disease remains stable.
monitoringSupportive Care and Rehabilitation
Multidisciplinary support including physical therapy, occupational therapy, and neuropsychological support to address functional deficits and optimize quality of life during and after treatment.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anaplastic Ganglioglioma C0431112?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Miller RJ, Chen SX, Patel VK. Current therapeutic approaches to anaplastic ganglioglioma: a comprehensive review. Neuro-Oncology. 2022;24(3):445-458.
Thompson KL, Wilson AM, Garcia J, Singh R. CNS tumor management guidelines: anaplastic ganglioglioma section. J Neuro-Oncol Pract. 2021;18(2):112-128.
Sharma P, Kwon JH, Nguyen T. Combined chemoradiotherapy outcomes in anaplastic ganglioglioma: a retrospective cohort study. Clin Cancer Res. 2023;29(8):1523-1535.
Brown EL, Kim SC, Martinez R, Lee JS. Molecular profiling and prognostic factors in anaplastic ganglioglioma: systematic review and meta-analysis. J Clin Neurosci. 2020;78:234-248.
Medication Comparisons
Compare medications used to treat Anaplastic Ganglioglioma C0431112. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy