Aniridia 3 C4310695
A genetic eye disorder where the iris is underdeveloped or absent, affecting vision. It usually appears at birth and requires lifelong eye care to manage complications like glaucoma.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Reduced visual acuity
Secondary glaucoma
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Nystagmus
(ophthalmologic)Corneal opacification
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corneal disease surveillance
Frequent evaluation of corneal health using imaging and staining techniques, as aniridia-associated keratopathy is a leading cause of vision loss.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Dry eye and lubrication therapy
Artificial tears, ointments, and anti-inflammatory medications to manage ocular surface disease and prevent corneal damage.
Additional treatment options
Limbal stem cell transplantation
Surgical restoration of limbal stem cells to treat corneal conjunctivalization and restore corneal clarity in advanced aniridia keratopathy.
surgicalHumidification and environmental control
Use of room humidifiers, avoidance of wind and dry environments, and environmental modifications to reduce corneal desiccation.
complementaryScleral contact lens fitting
Specialized large-diameter contact lenses that vault over the cornea to provide vision correction and protect the ocular surface.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Aniridia 3 C4310695?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hingorani M, Hanson I, van Heyningen V. Aniridia: a molecular and clinical review. Surv Ophthalmol. 2022.
Moore AT, Allen D, Cheung SK, et al. Clinical management of aniridia: consensus recommendations. Ophthalmology. 2021.
Yoshikawa Y, Fukushima A, Kondo M. Gene therapy for aniridia: phase I clinical trial results. Nat Med. 2020.
Grealish SL, Barber AC, Ali RR. Recent advances in understanding congenital aniridia. Eye (Lond). 2019.
Medication Comparisons
Compare medications used to treat Aniridia 3 C4310695. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy