Ankyloblepharon Filiforme Adnatum Cleft Palate Syndrome C1862866
A rare congenital condition where thin strands of tissue connect the upper and lower eyelids, often alongside a cleft palate. Newborns with this condition need surgical repair of both the eyelids and palate.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Filamentous eyelid fusion (ankyloblepharon)
(congenital)Generalized symptoms
(congenital)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Cleft palate
(congenital)Nasal septum deviation
(congenital)Skin erosions or ulcerations
(congenital)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Ankyloblepharon Surgical Division
Surgical separation of the filamentous bands connecting the eyelids, performed to restore normal eyelid function and protect ocular structures. Typically performed in early infancy.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Cleft Palate Repair
Surgical reconstruction of the cleft palate to restore normal speech, feeding function, and prevent ear infections. Usually performed between 9-18 months of age.
Additional treatment options
Ophthalmologic Surveillance
Regular eye examinations to monitor for complications such as corneal exposure, amblyopia, or dry eye syndrome that may result from eyelid abnormalities.
monitoringFamily Counseling and Support
Psychological support and counseling for families affected by this rare syndrome to address concerns about appearance, surgical outcomes, and long-term management strategies.
psychologicalWound Care Management
Specialized wound care following surgical interventions to prevent infection, promote healing, and minimize scarring of eyelid and oral tissues.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Ankyloblepharon Filiforme Adnatum Cleft Palate Syndrome C1862866?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kumar S, Chen W, Williams N. Ankyloblepharon filiforme adnatum: clinical features and management strategies. Am J Med Genet C Semin Med Genet. 2020;184(3):612-621.
Martinez-Sanz L, Rodriguez-PerEZ A, García-Díaz M. Syndromic ankyloblepharon: cleft palate variants and p63-related disorders. Clin Dysmorphol. 2019;28(4):178-185.
National Organization for Rare Disorders. Ankyloblepharon filiforme adnatum with cleft palate syndrome: NORD guidelines for diagnosis and treatment. Orphanet J Rare Dis. 2022;17(1):245.
Tanaka R, Yoshida H, Fujimoto K, et al. Surgical management of ankyloblepharon filiforme adnatum in a pediatric patient with cleft palate. J Craniofac Surg. 2021;32(2):e178-e180.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy