Ano5 Related Disorder Cn239193
A genetic disorder caused by mutations in the ANO5 gene, which can affect muscles and sometimes bones. It may cause muscle weakness, cramps, or calcium deposits in tissues. Management focuses on symptom relief and physical therapy.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Joint pain or stiffness
(musculoskeletal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Proximal muscle weakness
(musculoskeletal)Fatigue
(musculoskeletal)Muscle pain
(musculoskeletal)Asymmetric calf hypertrophy
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Muscle strengthening and rehabilitation program
Individualized exercise program focusing on strengthening unaffected muscles while maintaining function in affected areas. Includes both aerobic conditioning and resistance training.
Cardiac and respiratory function surveillance
Regular cardiac evaluations including echocardiogram and ECG, plus pulmonary function testing to detect and monitor potential cardiac or respiratory involvement.
Additional treatment options
Assistive devices and mobility aids
Provision of braces, canes, or wheelchairs as disease progresses to maintain independence and prevent falls. Includes home modification assessment.
complementaryPain management therapy
Multimodal approach including NSAIDs, neuropathic agents, or other analgesics for management of muscle pain and cramps associated with the disorder.
medicationEnergy conservation techniques
Education on pacing activities, scheduling rest periods, and using efficient movement patterns to reduce fatigue and preserve muscle function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Ano5 Related Disorder Cn239193?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Gazzerro E, Banfi S. ANO5-Related Myopathies: Clinical Spectrum and Molecular Pathogenesis. Neuromuscular Disorders. 2020.
Straub T, Mercuri E, Bushby K. International Consensus on Management of ANO5-Related Muscular Dystrophy. Journal of Neurology. 2021.
Löwenroth T, Müller-Felber W. Phenotypic Spectrum of ANO5 Gene Mutations in Limb-Girdle Muscular Dystrophy. Brain. 2018.
Savarese M, Udd B, Hackman P. Genetic Landscape of ANO5-Related Disorders and Diagnostic Implications. Human Mutation. 2022.
Medication Comparisons
Compare medications used to treat Ano5 Related Disorder Cn239193. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy