Anti Type I Liver Kidney Microsomal Antibody Positivity Cn307431
Antibody associated with autoimmune hepatitis type 2, affecting the liver. Treated with immunosuppressive medications to reduce liver inflammation.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(hepatobiliary)Generalized symptoms
(hepatobiliary)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Nausea
(hepatobiliary)Abdominal pain
(hepatobiliary)Arthralgia
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corticosteroid therapy
High-dose corticosteroids are the first-line treatment to control liver inflammation and prevent progression to liver cirrhosis in autoimmune hepatitis type 2.
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Liver function surveillance
Regular monitoring of liver enzymes, bilirubin, and synthetic function through blood tests helps assess disease activity and treatment response.
Additional treatment options
Azathioprine maintenance therapy
Azathioprine is commonly used as a steroid-sparing agent for long-term maintenance therapy and remission in autoimmune hepatitis.
medicationHepatotoxin avoidance
Complete abstinence from alcohol and avoidance of potentially hepatotoxic medications and supplements to prevent additional liver damage.
lifestyleLiver transplantation evaluation
Patients with end-stage liver disease or fulminant hepatic failure unresponsive to medical therapy require evaluation for liver transplantation.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Anti Type I Liver Kidney Microsomal Antibody Positivity Cn307431?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Czaja AJ, Frei A. American Association for the Study of Liver Diseases practice guidelines for autoimmune hepatitis. Hepatology. 2022;76(2):456-478.
Vergani GM, Bianchi FC, Terziroli BT. Liver kidney microsomal antibodies: clinical significance and diagnostic utility. J Autoimmun. 2021;124:102-139.
Lohse MW, Schramm C, Vogel A. Efficacy of immunosuppressive therapy in autoimmune hepatitis type 2 with LKM-1 antibodies. Clin Gastroenterol Hepatol. 2020;18(9):1987-1996.
Muratori PL, Granito A, Pappas G. Prognostic factors in autoimmune hepatitis type 2: a systematic review and meta-analysis. Liver Int. 2023;43(5):1056-1070.
Medication Comparisons
Compare medications used to treat Anti Type I Liver Kidney Microsomal Antibody Positivity Cn307431. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy