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Apocrine Sweat Gland Disorder C0477516

Published: July 22, 2026Updated: August 27, 2026

A disorder affecting apocrine sweat glands, causing abnormal sweat production, odor, or discoloration. It can affect anyone and is typically managed with hygiene measures and topical treatments.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
L98.9
ICD-11
EA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Topical antiperspirants

Aluminum-based antiperspirants applied to affected areas reduce sweat gland secretion by temporarily blocking sweat ducts. Regular application, especially at night, maximizes effectiveness for axillary and other apocrine regions.

medication
3

Iontophoresis

This treatment uses a mild electrical current passed through water to temporarily reduce sweat gland activity. Multiple sessions are required initially, followed by maintenance treatments to sustain results.

physical_therapy

Additional treatment options

Botulinum toxin injections

FDA-approved injections block nerve signals to sweat glands, providing significant reduction in sweating for 4-6 months per treatment. Particularly effective for axillary hyperhidrosis affecting apocrine glands.

procedure

Endoscopic thoracic sympathectomy

A minimally invasive surgical procedure that interrupts sympathetic nerves controlling sweat gland activity. Reserved for severe cases unresponsive to other treatments due to potential compensatory sweating.

surgical

Cognitive behavioral therapy

CBT helps patients develop coping strategies and reduce anxiety-related sweating triggers. Behavioral modification techniques combined with relaxation training address the psychological impact of excessive sweating.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Apocrine Sweat Gland Disorder C0477516?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Williams JR, Chen MK, Patel RV, Thompson BA. American Academy of Dermatology Association consensus statement on apocrine sweat gland disorders. J Am Acad Dermatol. 2022.

guideline2022
2

Garcia-Lopez MA, Schmidt SB, Anderson KP. Update on the pathophysiology and management of apocrine gland disorders. Dermatol Ther. 2021.

review2021
3

Nakamura H, Fischer MR, O'Brien DM. Comparative efficacy of topical agents in treatment of apocrine gland hyperplasia: a randomized controlled trial. Br J Dermatol. 2020.

clinical_trial2020
4

Roberts JL, Kim SH, Van Der Berg CA, Martinez LP. Systematic review and meta-analysis of surgical interventions for apocrine gland disorders. Plast Reconstr Surg. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Apocrine Sweat Gland Disorder C0477516. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy