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Aquagenic Palmoplantar Keratoderma C4087301

Published: July 22, 2026Updated: August 20, 2026

A rare skin condition where contact with water causes temporary thickening and wrinkling of the skin on palms and soles. Symptoms can be managed with moisturizers and protective measures.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q84.9
ICD-11
LA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Medication Comparisons

Compare medications used to treat Aquagenic Palmoplantar Keratoderma C4087301. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy