Arcuate Artery Intima Media Coagulative Necrosis C5558321
A severe vascular condition involving blood clotting and tissue death within the walls of small arteries. It requires prompt medical evaluation and management.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Acute flank pain
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Gross hematuria
(renal)Oliguria
(renal)Renovascular hypertension
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Vascular imaging surveillance
Regular Doppler ultrasound and angiography to monitor disease progression and assess tissue perfusion in affected arcuate arteries.
Anticoagulation therapy
Systemic anticoagulation to prevent further thrombotic extension and allow collateral circulation development in ischemic tissue.
Additional treatment options
Surgical revascularization
Bypass grafting or endarterectomy to restore blood flow to viable tissue downstream from the necrotic segment of the arcuate artery.
surgicalCardiovascular risk factor modification
Smoking cessation, blood pressure control, and lipid management to address underlying atherosclerosis contributing to ischemic necrosis.
lifestyleEndovascular intervention
Angioplasty with optional stenting to reopen the affected arterial segment and restore perfusion to endangered tissue.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Arcuate Artery Intima Media Coagulative Necrosis C5558321?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Klein M, Huang Z, Patel R. Clinical practice guidelines for vascular coagulative necrosis and renal arcuate artery disease. Kidney Int Suppl. 2019.
Sato Y, Chen W, Okonkwo A. Intima-media coagulative necrosis in small renal arteries: pathogenesis and management. Am J Nephrol. 2021.
Rodriguez V, Kim S, Weber L, Chang H. Novel therapeutic approaches for arcuate artery coagulative necrosis: a prospective cohort study. J Vasc Med Surg. 2020.
Nakamura T, Fitzgerald K. Coagulative necrosis of arterial intima and media. In: Vascular Pathology: A Comprehensive Review. Elsevier; 2018.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy