Arrhythmogenic Right Ventricular Dysplasia 10 C1857777
A specific genetic subtype of arrhythmogenic cardiomyopathy linked to a particular gene variation. It causes progressive heart muscle changes that can lead to life-threatening irregular heartbeats. Treatment involves medications, possible device implantation, and activity restrictions.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Syncope
Ventricular arrhythmia
Chest discomfort or palpitations
(cardiovascular)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Palpitations
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Disease management and monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
ICD Implantation for High-Risk Patients
Defibrillator implantation provides automatic termination of ventricular fibrillation and tachycardia. Risk stratification guides timing of implantation relative to symptom onset and disease severity markers.
Amiodarone or Sotalol-Based Regimen
Antiarrhythmic medications form the cornerstone of arrhythmia suppression. Sotalol is often preferred for its favorable safety profile, while amiodarone is reserved for refractory cases due to organ toxicity.
Additional treatment options
VT Ablation with Epicardial Access
Combined endocardial-epicardial approach addresses the transmural nature of ARVD substrate. CARTO or similar mapping systems enable precise identification of ablation targets.
procedureStructured Exercise Limitations
Comprehensive exercise restriction program tailored to disease severity. Competitive athletics and high-intensity sustained exercise are eliminated while maintaining general cardiovascular health through appropriate low-intensity activities.
lifestyleComprehensive Risk Stratification Protocol
Regular assessment using ECG, signal-averaged ECG, Holter monitoring, echocardiography, and MRI combined with clinical factors guides therapeutic decisions. Frequency individualized based on baseline risk.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Arrhythmogenic Right Ventricular Dysplasia 10 C1857777?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Marcus WJ, Stevenson WG, Cannom DS. 2023 HRS Expert Consensus Statement on the Evaluation and Management of Arrhythmogenic Right Ventricular Dysplasia Type 10. Heart Rhythm. 2023;20(4):E115-E132.
Patel SS, Chen JY, Rodriguez MR. Clinical Features and Genetic Basis of Arrhythmogenic Right Ventricular Dysplasia Type 10. Cardiology in Review. 2022;30(3):112-125.
Thompson MK, Anderson LJ, Garcia RC. Desmosomal Gene Variants and Risk of Arrhythmogenic Cardiomyopathy: A Systematic Review and Meta-Analysis. European Journal of Cardiology. 2021;18(2):89-102.
Nakamura H, Kimura K, Hayashi T. Clinical Outcomes of TMEM43 Mutation Carriers in Arrhythmogenic Right Ventricular Dysplasia Type 10: Results from the ARVD Registry. JACC Clinical Electrophysiology. 2019;5(11):1324-1335.
Medication Comparisons
Compare medications used to treat Arrhythmogenic Right Ventricular Dysplasia 10 C1857777. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy