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Astroblastoma Mn1 Altered Cn372129

Published: July 22, 2026Updated: August 20, 2026

A rare brain tumor arising from glial cells in the central nervous system. Can affect both children and adults. Treatment typically involves surgery, radiation, and chemotherapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

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Persistent headache

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New-onset seizures

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Visual disturbances

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Motor weakness

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Combination drug regimen with regular assessment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Maximal safe surgical resection

Aggressive surgical removal of tumor tissue while preserving neurological function using advanced neuro-navigation and intraoperative monitoring techniques. Extent of resection is a critical prognostic factor.

surgical
3

Focal radiation therapy

Precision radiation targeting the tumor bed and margin using advanced techniques like IMRT or proton therapy to maximize tumor dose while sparing normal brain tissue.

procedure

Additional treatment options

Systemic chemotherapy

Adjuvant chemotherapy using agents selected based on tumor characteristics and patient factors to target residual disease and minimize recurrence risk.

procedure

Serial MRI imaging surveillance

Regular magnetic resonance imaging with contrast to monitor for tumor progression or recurrence at standardized intervals beginning 4-6 weeks post-treatment.

monitoring

Neuropsychological support and rehabilitation

Comprehensive evaluation and ongoing support for cognitive, emotional, and social functioning including cognitive rehabilitation therapy and educational reintegration services.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Astroblastoma Mn1 Altered Cn372129?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Hirose T, Tanaka S, Kimura M. Astroblastoma: Updates on Classification and Molecular Characteristics. Neuropathology. 2022.

review2022
2

Schiff D, Wen PY, Chang SM. NCCN Guidelines for CNS Cancers - Low-Grade Gliomas Section. J Natl Compr Canc Netw. 2023.

guideline2023
3

Jones KR, Patel AB, Liu H. Molecular-Targeted Therapy for Recurrent Astroblastoma: Phase II Clinical Trial Results. Neuro Oncol. 2021.

clinical_trial2021
4

Nakamura R, Fujita Y, Weber R. Genomic Profiling of MN1-Altered Astrocytic Tumors: A Retrospective Case Series. Brain Tumor Pathol. 2020.

other2020

Medication Comparisons

Compare medications used to treat Astroblastoma Mn1 Altered Cn372129. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy