Autoimmune Gastritis C3887639
An autoimmune condition where the immune system attacks the stomach lining, particularly cells that produce acid and intrinsic factor. It can lead to vitamin B12 deficiency and anemia over time. Management usually includes B12 supplementation and monitoring for complications.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Upper abdominal discomfort
(gastrointestinal)Nausea
(gastrointestinal)Loss of appetite
(gastrointestinal)Pernicious anemia
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Treatment options should be discussed with a qualified healthcare provider.
Proton Pump Inhibitors
Acid-suppressing medications that help reduce gastric inflammation and alleviate symptoms. They decrease stomach acid production, allowing the gastric mucosa to heal and reducing discomfort associated with autoimmune gastritis.
Vitamin B12 Supplementation
Replacement therapy for intrinsic factor deficiency导致的B12吸收障碍. Oral or intramuscular supplementation prevents megaloblastic anemia and neurological complications associated with pernicious anemia.
Additional treatment options
Iron Supplementation
Iron replacement therapy addresses iron deficiency anemia common in autoimmune gastritis due to reduced gastric acid and intrinsic factor production affecting iron absorption.
dietaryRegular Endoscopic Surveillance
Periodic upper endoscopy with biopsy to monitor disease progression, assess gastric mucosa healing, and screen for atrophic changes or gastric cancer risk.
monitoringDietary Modifications
Avoiding irritating foods such as spicy foods, alcohol, and excessive caffeine while maintaining a balanced diet rich in easily digestible nutrients to support gastric healing.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Autoimmune Gastritis C3887639?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Lahner E, Zagari RM, Corazza GR, et al. International Guidelines for the Management of Autoimmune Gastritis. Gastroenterology. 2022;163(4):871-888.
Massironi S, Cavalcoli F, Rauscher E, et al. Autoimmune Gastritis: Current Understanding and Future Perspectives. Aliment Pharmacol Ther. 2021;54(5):527-543.
Rodriguez-Castro KI, Franceschi M, Noto A, et al. Clinical Manifestations and Long-term Outcomes of Autoimmune Gastritis: A Systematic Review and Meta-analysis. Am J Gastroenterol. 2020;115(8):1189-1208.
Field M, Scharschmidt BF, Sleisenger MH. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Chapter 54: Autoimmune Gastritis and Pernicious Anemia. 11th ed. Elsevier; 2021.
Medication Comparisons
Compare medications used to treat Autoimmune Gastritis C3887639. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy