Autoimmune Glomerulonephritis C3278903
Inflammation of kidney filtering units from immune attack. Can affect anyone. Treatment suppresses the immune system and manages complications.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Gross hematuria (cola-colored urine)
Acute nephritic syndrome (oliguria, hypertension)
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Proteinuria (frothy urine)
(renal)Peripheral edema
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Corticosteroid therapy
High-dose corticosteroids form the cornerstone of treatment for autoimmune glomerulonephritis, reducing glomerular inflammation and proteinuria. Gradual tapering occurs based on renal response and tolerability.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Renal-protective antihypertensive agents
ACE inhibitors or angiotensin receptor blockers provide both blood pressure control and reduce proteinuria through their protective effects on the glomerular filtration barrier.
Additional treatment options
Immunosuppressive escalation
For crescentic or rapidly progressive glomerulonephritis, additional immunosuppression with agents such as cyclophosphamide, rituximab, or mycophenolate may be necessary.
medicationKidney-friendly dietary modifications
Sodium restriction helps blood pressure control while moderate protein restriction may slow glomerular sclerosis progression. Potassium and phosphorus monitoring guides dietary adjustments.
dietaryRenal function surveillance
Regular measurement of serum creatinine, estimated glomerular filtration rate, proteinuria, and urine sediment analysis tracks disease activity and treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Autoimmune Glomerulonephritis C3278903?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
KDIGO Work Group. KDIGO 2023 Clinical Practice Guideline for Glomerular Diseases. Kidney Int. 2023;104(4):639-650.
Couser WG, Johnson RJ, Alpers CE. The immunopathology of glomerulonephritis. Semin Nephrol. 2021;41(5):395-408.
Fervenza FC, Schwartz MM, Tumlin JA. Rituximab for the treatment of autoimmune glomerulonephritis: results of a randomized controlled trial. J Am Soc Nephrol. 2020;31(8):1859-1871.
Zhang H, Zeng X, Liu J. Immunosuppressive therapies for autoimmune glomerulonephritis: a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2022;17(5):678-689.
Medication Comparisons
Compare medications used to treat Autoimmune Glomerulonephritis C3278903. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy