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Autoimmune Pancreatitis Type 1 C4302243

Published: July 22, 2026Updated: August 20, 2026

A form of chronic pancreatitis caused by an autoimmune inflammatory process, often associated with elevated IgG4 levels. It typically affects older adults and is more common in men. Most patients respond well to corticosteroid therapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
K30
ICD-11
DA00.0
Body system
gastrointestinal
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Abdominal pain or nausea

(gastrointestinal)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Jaundice

(gastrointestinal)

Back pain

(gastrointestinal)

Weight loss

(gastrointestinal)

Steatorrhea

(gastrointestinal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Corticosteroid Therapy

High-dose oral corticosteroids serve as the primary treatment to suppress inflammatory response, reduce pancreatic swelling, and restore exocrine and endocrine function in type 1 autoimmune pancreatitis.

medication
2

GI disease management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Immunomodulatory Agents

Steroid-sparing immunosuppressants such as azathioprine are used for maintenance therapy and to prevent relapse after initial corticosteroid treatment, reducing long-term steroid exposure.

medication

Additional treatment options

Endoscopic Retrograde Cholangiopancreatography

ERCP procedure to relieve biliary obstruction when autoimmune pancreatitis affects the bile ducts, allowing for stenting and drainage while diagnostic tissue samples are obtained.

procedure

Pancreatic Enzyme Replacement

Supplemental pancreatic enzymes help maintain adequate nutrition when exocrine function is compromised, improving fat and protein digestion and reducing steatorrhea symptoms.

dietary

Imaging and Tumor Marker Surveillance

Regular CT or MRI imaging combined with serum CA-199 monitoring helps distinguish between inflammatory mass and malignancy, with surveillance continued even after remission.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Autoimmune Pancreatitis Type 1 C4302243?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Shimosegawa T, Chari ST, Frulloni L, et al. International consensus diagnostic criteria for autoimmune pancreatitis type 1. Pancreas. 2011.

guideline2011
2

Kamisawa T, Zen Y, Pillai S, Stone JH. IgG4-related disease. Lancet. 2015.

review2015
3

Kubota K, Iida H, Fujisawa T, et al. Clinical trial of corticosteroid therapy for autoimmune pancreatitis. Gut. 2013.

clinical_trial2013
4

Hart PA, Topazian MD, Witzig TE, et al. Treatment of relapsing autoimmune pancreatitis with immunomodulators. Clin Gastroenterol Hepatol. 2014.

review2014

Medication Comparisons

Compare medications used to treat Autoimmune Pancreatitis Type 1 C4302243. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy