Autosomal Dominant Isolated Diffuse Palmoplantar Keratoderma C5680349
A genetic skin condition causing thickened skin on the palms and soles due to excessive keratin production. Inherited in families and present from birth or early life. Softening creams and sometimes surgical options may help.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy