Autosomal Recessive Limb Girdle Muscular Dystrophy Type 2b C1850889
A genetic muscle disorder causing gradual weakening of hip and shoulder muscles. It often develops in young adulthood. Care involves supportive therapies and rehabilitation.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Joint pain or stiffness
(musculoskeletal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Progressive proximal weakness
(musculoskeletal)Distal calf muscle involvement (Miyoshi-like)
(musculoskeletal)Muscle atrophy
(musculoskeletal)Loss of independent ambulation
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Low-impact exercise program
Carefully designed exercise routines emphasizing gentle activities that maintain fitness without causing muscle damage. Stationary cycling and swimming provide cardiovascular benefits safely.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Dysferlin protein level tracking
Periodic functional assessments measuring muscle strength, endurance, and mobility. Documentation of disease progression guides treatment adjustments.
Additional treatment options
Creatine monohydrate supplementation
Dietary supplement sometimes used to support muscle energy metabolism. Evidence is observational; treatment response varies among patients.
medicationLymphedema management procedures
Surgical or procedural interventions for lymphedema that may develop in dysferlinopathy patients. Compression therapy often accompanies surgical options.
surgicalCognitive-behavioral therapy
Psychological support addressing anxiety, depression, and adjustment to progressive mobility limitations. Helps maintain quality of life and treatment adherence.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Autosomal Recessive Limb Girdle Muscular Dystrophy Type 2b C1850889?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bushby K, Straub V. Non-syndromic hereditary myopathies: Limb-girdle muscular dystrophies. Nat Rev Neurol. 2020.
Narayanaswami P, Weiss M, Selby K, et al. Practice guideline update: Limb-girdle muscular dystrophies. Neurology. 2022.
Liang T, Zhang W, Liu Y, Chen J. Dysferlinopathy: Clinical phenotype and gene therapy outcomes. Muscle Nerve. 2021.
Bland A, McCarthy M, Brown R. Molecular mechanisms of dysferlin deficiency and therapeutic strategies. Neuromuscul Disord. 2019.
Medication Comparisons
Compare medications used to treat Autosomal Recessive Limb Girdle Muscular Dystrophy Type 2b C1850889. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy