Autosomal Recessive Spastic Paraplegia Type 66 C5190590
A genetic disorder affecting the nervous system, leading to progressive leg stiffness and weakness. Both parents typically carry the gene. Treatment focuses on physical therapy and symptom management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Lower limb spasticity
(neurologic)Progressive spastic paraplegia
(neurologic)Hyperreflexia
(neurologic)Pes cavus
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy