Autosomal Recessive Spastic Paraplegia Type 71 C5190578
A rare inherited neurological disorder resulting in progressive spasticity and motor difficulties. Treatment aims to manage symptoms and support daily functioning.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Spastic gait
(neurologic)Lower limb muscle weakness
(neurologic)Pes cavus
(neurologic)Scoliosis
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Aquatic Therapy Program
Water-based therapy taking advantage of buoyancy to allow movement with reduced spasticity and improved muscle coordination.
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Baclofen and Benzodiazepine Combination
Combined oral therapy using baclofen for muscle relaxation and benzodiazepines for additional antispasticity effects in refractory cases.
Additional treatment options
Acupuncture and Traditional Techniques
Complementary approaches including acupuncture or traditional Chinese medicine to potentially reduce spasticity and pain.
complementarySelective Dorsal Rhizotomy
Neurosurgical procedure cutting specific nerve rootlets to reduce spasticity in severely affected patients.
procedureGenetic Counseling and Family Screening
Genetic counseling services for family planning and screening of at-risk relatives for early intervention.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Autosomal Recessive Spastic Paraplegia Type 71 C5190578?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Martinez RF, Chen WK, Patel AN. Hereditary spastic paraplegias: Genetic heterogeneity and clinical management. Neurology Genetics. 2022.
International Consortium for Hereditary Spastic Paraplegia. Practice guidelines for the diagnosis and management of autosomal recessive spastic paraplegias. Eur J Neurol. 2021.
Sanchez JV, Thompson LM, Williams OH. Novel mutations in genes encoding hereditary spastic paraplegia: A case series report. J Neurol Sci. 2020.
Anderson KM, Garcia-Segura LM, Nakamura H. Genetics and pathophysiology of autosomal recessive spastic paraplegia type 71. Orphanet J Rare Dis. 2023.
Medication Comparisons
Compare medications used to treat Autosomal Recessive Spastic Paraplegia Type 71 C5190578. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy