B Cell Lymphoma C0079731
A cancer that develops in infection-fighting white blood cells called B cells. It can affect both children and adults, with treatment options including chemotherapy, immunotherapy, and radiation depending on the specific type.
Key facts at a glance
- ICD-10
- C83.00, C83.01, C83.02
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Painless lymphadenopathy
(oncologic)B symptoms (fever, night sweats, weight loss)
(oncologic)Fatigue
(oncologic)Hypercalcemia
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Chemoimmunotherapy
Combination of chemotherapy agents with monoclonal antibody immunotherapy (typically rituximab) forming the standard first-line treatment. R-CHOP regimen is most commonly used for aggressive B-cell lymphomas.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Targeted Therapy Agents
Use of novel agents such as polatuzumab vedotin or bispecific antibodies for relapsed or refractory disease. These therapies target specific markers on B-cell lymphoma cells with greater precision.
medicationRadiation Therapy
Localized radiation treatment used for early-stage disease or palliative symptom control. May be combined with chemotherapy in certain presentations.
procedureAutologous Stem Cell Transplant
High-dose chemotherapy followed by rescue with patient's own collected stem cells. Considered for patients achieving remission who are at high risk for relapse.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is B Cell Lymphoma C0079731?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 2014.
Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016.
Coiffier B, Lepage E, Briere J, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma. N Engl J Med. 2002.
Schuster SJ, Bishop MR, Tam CS, et al. Tisagenlecleucel in adult relapsed or refractory diffuse large B-cell lymphoma. J Clin Oncol. 2019.
Medication Comparisons
Compare medications used to treat B Cell Lymphoma C0079731. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy