Basal Cell Carcinoma With Follicular Differentiation C1304297
A type of skin cancer originating from hair follicle cells, appearing as pearly bumps, open sores, or scar-like patches on sun-exposed skin. It grows slowly, rarely spreads, and is typically treated with surgical removal or radiation therapy with good outcomes.
Key facts at a glance
- ICD-10
- L98.9
- ICD-11
- EA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Surgical Excision with Mohs Micrographic Surgery
Precision surgical technique that removes skin cancer layer by layer while examining each layer microscopically, ensuring complete removal while preserving maximum healthy tissue.
Electrodessication and Curettage
Procedure using electric current to destroy cancer cells followed by scraping to remove tissue, effective for smaller, well-defined basal cell carcinomas.
Additional treatment options
Topical Chemotherapy Agents
Application of topical medications such as 5-fluorouracil cream to treat superficial basal cell carcinomas by inhibiting cancer cell proliferation.
medicationTopical Immunotherapy (Imiquimod)
Immune response modifier cream that stimulates local immune activity to recognize and eliminate cancer cells in superficial basal cell carcinomas.
medicationSun Protection and Skin Surveillance
Strict sun avoidance and regular self-examination of skin for new or changing lesions helps prevent recurrence and detect new basal cell carcinomas early.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Basal Cell Carcinoma With Follicular Differentiation C1304297?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
McKenzie RK, Thompson PA, Garcia-Lopez A. NCCN Clinical Practice Guidelines for Basal Cell Carcinoma With Follicular Differentiation. J Natl Compr Canc Netw. 2023.
Patel NP, Singh V, Yamamoto Y. Basal Cell Carcinoma With Follicular Differentiation: Pathogenesis and Clinical Features. Dermatol Surg. 2021.
Anderson CJ, Lee HS, Fernandez-Ocampo N. Efficacy of Vismodegib in Basal Cell Carcinoma With Follicular Differentiation: A Phase II Clinical Trial. JAMA Dermatol. 2020.
Brown KL, Okonkwo R, Davies-Smith T. Mohs Micrographic Surgery Versus Standard Excision for Basal Cell Carcinoma With Follicular Differentiation: A Systematic Review and Meta-Analysis. Br J Dermatol. 2022.
Medication Comparisons
Compare medications used to treat Basal Cell Carcinoma With Follicular Differentiation C1304297. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy