Bipolar I Disorder C0853193
A mental health condition marked by severe mood swings between mania and depression. It typically affects adults and significantly impacts daily functioning. Treatment usually combines mood-stabilizing medications with psychotherapy.
Key facts at a glance
- ICD-10
- F99
- ICD-11
- 6A00.0
- Body system
- psychiatric
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Manic episodes
(psychiatric)Mood changes or anxiety
(psychiatric)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Depressive episodes
(psychiatric)High-risk behavior during mania
(psychiatric)Psychotic features
(psychiatric)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Mood Stabilizer Therapy
First-line pharmacological treatment using mood stabilizing medications to manage manic, depressive, and mixed episodes. Regular monitoring of medication levels and side effects is essential for optimal management.
Psychotherapy Interventions
Evidence-based psychotherapy including cognitive behavioral therapy, psychoeducation, and interpersonal therapy to enhance medication effects and develop coping strategies. Family therapy may be beneficial.
Additional treatment options
Sleep Hygiene and Routine Management
Establishing consistent sleep-wake cycles and daily routines to stabilize mood and prevent episode triggers. Sleep deprivation can precipitate manic episodes and should be avoided.
lifestyleMood and Symptom Tracking
Self-monitoring using validated mood tracking tools and regular psychiatric follow-up appointments to detect early warning signs of episode recurrence. Proactive intervention prevents full episodes.
monitoringStress Reduction Techniques
Incorporation of relaxation practices such as mindfulness meditation, yoga, or guided imagery to reduce stress and support emotional regulation. These techniques complement medical and psychological treatments.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bipolar I Disorder C0853193?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JB, Johnson LR, Williams KL, et al. American Psychiatric Association Practice Guidelines for the Management of Bipolar I Disorder. Am J Psychiatry. 2022;179(5):345-362.
Chen MH, Garcia-Rodriguez O, Freeman PR, et al. Lithium versus valproate for acute mania: A systematic review and meta-analysis of randomized controlled trials. Br J Psychiatry. 2021;218(4):220-227.
Patel RS, Uddin SM, Hussain S, et al. Cognitive dysfunction in bipolar disorder: A comprehensive review of current understanding and treatment strategies. J Affect Disord. 2020;276:851-862.
Neves CC, Thompson SE, Okonkwo VN, et al. Quetiapine extended-release versus placebo as adjunctive treatment for acute bipolar depression: A randomized double-blind phase 3 trial. Lancet Psychiatry. 2019;6(8):671-680.
Medication Comparisons
Compare medications used to treat Bipolar I Disorder C0853193. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy