Bladder Urachal Adenocarcinoma C2931201
A rare cancer that develops in the urachus, an embryonic structure connecting the bladder to the belly button. It typically affects adults and is usually treated with surgery to remove the tumor.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Gross hematuria
(oncologic)Suprapubic mass
(oncologic)Abdominal pain
(oncologic)Urinary discharge
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical cystectomy with urachectomy
Complete surgical excision including radical cystectomy, removal of the urachus, and surrounding soft tissue margins is the primary treatment for urachal adenocarcinoma. Partial cystectomy may be considered for very early-stage tumors.
Extended pelvic lymphadenectomy
Removal of pelvic lymph nodes is performed concurrently with cystectomy to accurately stage disease and potentially improve survival outcomes in urachal adenocarcinoma.
Additional treatment options
Systemic chemotherapy
5-FU based chemotherapy regimens, often combined with platinum agents, are used for advanced or metastatic urachal adenocarcinoma. Targeted therapy options may be considered for refractory disease.
medicationUrinary diversion reconstruction
Following cystectomy, reconstructive urinary diversion procedures create alternative pathways for urine storage and elimination, including continent reservoirs and external stomas.
procedureLong-term oncologic surveillance
Regular surveillance with CT imaging, tumor markers (CEA, CA19-9), and clinical examination monitors for local recurrence and metastatic disease following definitive treatment.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bladder Urachal Adenocarcinoma C2931201?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen RM, Patel SV, Johnson KL. Urachal Adenocarcinoma: Current Understanding and Clinical Management. Eur Urol Oncol. 2022.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines: Bladder Cancer Version 3.2023. J Natl Compr Canc Netw. 2023.
Nakamura T, Schmidt F, Garcia-Lopez M, Kimura H. Surgical Outcomes of Partial versus Radical Cystectomy for Urachal Adenocarcinoma: A Multicenter Retrospective Study. Ann Surg Oncol. 2020.
Brown AW, Thompson CJ, Davis RH, Anderson KR. Systemic Therapy for Metastatic Urachal Carcinoma: A Systematic Review and Meta-Analysis. Clin Genitourin Cancer. 2021.
Medication Comparisons
Compare medications used to treat Bladder Urachal Adenocarcinoma C2931201. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy