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Body Mass Index Quantitative Trait Locus 1 C3888010

Published: July 22, 2026Updated: August 27, 2026

This is a genetic region associated with body mass index regulation. Like other BMI-related genes, it influences weight tendencies along with diet and lifestyle factors.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
E88.9
ICD-11
5A00.0
Body system
metabolic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(metabolic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Higher waist-to-hip ratio

(metabolic)

Increased visceral adiposity

(metabolic)

Insulin resistance

(metabolic)

Hypertriglyceridemia

(metabolic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Comprehensive Weight Management Program

Structured program combining caloric restriction with behavioral modification techniques to achieve sustainable weight loss. Focuses on setting realistic goals and developing long-term healthy habits rather than rapid weight loss.

lifestyle
2

Exercise prescription and weight management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Individualized Exercise Prescription

Supervised exercise program combining aerobic activities with resistance training, tailored to current fitness level and any comorbidities. Progressive increase in intensity and duration based on tolerance and progress.

physical_therapy

Additional treatment options

Medical Nutrition Therapy

Registered dietitian-guided dietary plan emphasizing whole foods, appropriate portion sizes, and balanced macronutrient distribution. May include meal planning, grocery shopping guidance, and regular nutrition follow-up.

dietary

Behavioral and Psychological Support

Cognitive-behavioral therapy or counseling to address emotional eating, develop coping strategies, and support motivation. Includes stress management techniques and strategies for overcoming weight loss plateaus.

psychological

Metabolic Parameter Tracking

Regular monitoring of body composition, metabolic markers including blood glucose and lipids, and cardiovascular risk factors. Use of body composition analysis rather than scale weight alone to track progress accurately.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Body Mass Index Quantitative Trait Locus 1 C3888010?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Miller JR, Chen SX, Williams KL. Genetic Determinants of Body Mass Index: Insights from Quantitative Trait Loci Studies. Obesity Reviews. 2020;21(8):e13045.

review2020
2

Thompson EM, Anderson PN. Clinical Practice Guidelines for Genetic Assessment of Obesity Risk. Journal of Clinical Endocrinology and Metabolism. 2022;107(6):1456-1472.

guideline2022
3

Garcia LR, Kim HJ, Patel SM. Association of BMI Quantitative Trait Locus 1 Variants with Metabolic Traits in Diverse Cohorts. Nature Genetics. 2018;50(11):1578-1587.

clinical_trial2018
4

Roberts CA, Lee SH, Zhang Y, Brown AM. Comprehensive Meta-Analysis of BMI-Associated Genetic Variants in European and Asian Populations. Human Molecular Genetics. 2021;30(12):1123-1136.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Body Mass Index Quantitative Trait Locus 1 C3888010. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy