C1q Nephropathy C0403434
A kidney disease linked to problems with the immune complement system. It can lead to protein in urine and kidney damage. Treatment focuses on controlling inflammation and protecting kidney function.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Proteinuria
(renal)Hematuria
(renal)Edema
(renal)Nephrotic syndrome
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunosuppressive therapy
Corticosteroids and other immunosuppressants to reduce glomerular inflammation and proteinuria. Treatment intensity based on disease severity and renal involvement.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Renin-angiotensin system blockade
ACE inhibitors or ARBs to control proteinuria and protect kidney function. Provides renoprotective effects beyond blood pressure management.
Additional treatment options
Renal function and proteinuria surveillance
Regular monitoring of serum creatinine, estimated GFR, urinary protein excretion, and albumin levels to assess disease progression and treatment response.
monitoringKidney-friendly dietary modifications
Sodium restriction, moderate protein intake, and balanced potassium and phosphorus management based on kidney function. May include supervised medical nutrition therapy.
dietaryRenal biopsy
Percutaneous kidney biopsy to confirm diagnosis, assess histological features, and guide treatment decisions when clinical picture is unclear.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
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Frequently asked questions
Common questions about this topic.
What is C1q Nephropathy C0403434?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy