Carcinoma In Situ Of Urethra C4721449
An early-stage cancer limited to the inner lining of the urethra, the tube that carries urine from the bladder. Surgical removal of affected tissue is typically performed.
Key facts at a glance
- ICD-10
- D02.1, D01.2, D07.1
- ICD-11
- 3A00.0
- Body system
- genitourinary
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Gross hematuria
Generalized symptoms
(genitourinary)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Dysuria
(genitourinary)Urethral discharge
(genitourinary)Weak urinary stream
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Transurethral resection of urethra
Endoscopic removal of carcinoma in situ of the urethra using specialized instruments passed through the urethra. Allows tissue diagnosis and complete excision of visible lesions.
Urethroscopic surveillance program
Regular endoscopic monitoring of the urethra for recurrence following treatment. Includes urine cytology and direct visualization at follow-up intervals.
Additional treatment options
Topical 5-fluorouracil therapy
Application of 5-FU cream directly to urethral mucosa to treat surface carcinoma in situ. This approach targets abnormal cells while minimizing systemic side effects.
procedureTopical BCG immunotherapy
Intraurethral instillation of BCG vaccine to stimulate local immune response against carcinoma in situ cells. May be used for refractory cases.
procedureUrethrectomy
Surgical removal of the urethra for extensive carcinoma in situ that cannot be controlled with conservative approaches. May be partial or total depending on disease extent.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Carcinoma In Situ Of Urethra C4721449?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy